研究兴趣

  不对称催化、天然产物全合成、药物化学

招生信息

  每年招收博士生1-2名，硕士生1-2名。 欢迎热爱科研、工作认真、积极向上的同学加入。研究背景要求：有机合成化学和药物化学。

代表性论文

1. Changgui Zhao, Zhengqing Ye, Zhi-xiong Ma, Scott A. Wildman, Stephaine A. Blaszczyk, Lihong Hu, Ilia A. Guizei, Weiping Tang*. A Diversification Strategy for the Synthesis of Polycyclic Scaffolds with Medium Sized Rings from Complex Natural Products. Nat. Commun. 2019, 10, 4015.

2. Changgui Zhao, Daniel A. Glazier, Daoshan Yang, Dan Yin, Ilia A. Guizei, Michael M. Aristov, Peng Liu*, Weiping Tang*. Intermolecular Regio- and Stereoselective hetero-[5+2] Cycloaddition between Oxidopyrylium Ylides and Cyclic Imines. Angew. Chem. Int. Ed. 2019, 58, 887.

3. Changgui Zhao, Donghui Guo, Kristin Munkerup, Kuo-Wei Huang, Fangyi Li, Jian Wang*. Enantioselective [3+3] Atroposelective Annulation Catalyzed by N-heterocyclic Carbenes. Nat. Commun. 2018, 9, 611.

4. Changgui Zhao, Xingang Xie, Shuangshuang Duan, Huilin Li, Ran Fang, Xuegong She*. Gold-Catalyzed 1,2-Acyloxy Migration/Intramolecular [3+2] 1,3-Dipolar Cycloaddtion Cascade Reaction: An Efficient Strategy for Syntheses of Medium-Sized-Ring Ethers and Amines. Angew. Chem. Int. Ed. 2014, 53, 10789.

5. Changgui Zhao, Fangyi Li, Jian Wang*. N-Heterocyclic Carbene Catalyzed Dynamic Kinetic Resolution of Pyranones. Angew. Chem. Int. Ed. 2016, 55, 1820.

6. Changgui Zhao, Jian Wang*. Divergent Synthesis of Dihydropyranone Stereoisomers via N-Heterocyclic Carbene Catalysis. Adv. Syn. Cat. 2019, 361, 1668.

7. Jicheng Wu, Changgui Zhao, Jian Wang. Enantioselective Intermolecular Enamide-Aldehyde Cross-Coupling Catalyzed by Chiral N-Heterocyclic Carbenes. J. Am. Chem. Soc. 2016, 138, 4706.

8. Changgui Zhao; Ziyun Yuan, Yuanyuan Zhang, Bin Ma, Huilin Li, Shouchu Tang, Xingang Xie*, Xuegong She*. Scalable, Efficient Total Synthesis of (+)-Mupirocin H. Org. Chem. Front. 2014, 1, 105.

9. Changgui Zhao, Huaiji Zheng, Peng Jing, Bowen Fang, Xingang Xie*, Xuegong She*. Tandem Oxidative Dearomatization/Intramolecular Diels-Alder Reaction for Construction of the Tricyclic Core of Palhinine A. Org. Lett. 2012, 14, 2293.